Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer

Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer

Indexed In: SCOPUS
Release Date: March, 2021|Copyright: © 2021 |Pages: 309
DOI: 10.4018/978-1-7998-3580-6
ISBN13: 9781799835806|ISBN10: 1799835804|EISBN13: 9781799835813
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Description & Coverage
Description:

In recent years, epidemiological studies have shown a significant increase of incidences regarding ulcerative colitis (UC) in most regions of the world. At present, a common therapeutic modality for inflammatory bowel disorders is the use of anti-inflammatory agents, including sulfasalazine and acetylsalicylic acid, steroid hormone, and other immunosuppressive agents. Most of these treatments are symptomatic and palliative because the etiology of the disease is not yet established. As a result of no proper drug available to treat UC, patients with UC are at a high risk of developing colitis-associated cancer (CAC). It is necessary to understand the genetic and molecular mechanisms involved in the pathogenesis of UC and CAC that lead to the path of new drug discoveries.

Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer provides innovative insights that describe the fundamental understanding of UC and CAC and the molecular mechanisms behind the etiology as well as modern diagnostic methods that are employed in UC and CAC. Current prevention and therapeutic strategies practiced in the pre-clinical level are also discussed. The content within this publication examines alternative medicine and dietary intervention and drug delivery techniques. It is designed for healthcare professionals, physicians, academicians, researchers, R&D organizations, and medical students involved in drug discovery and clinical and therapeutic research.

Coverage:

The many academic areas covered in this publication include, but are not limited to:

  • Alternative Medicine
  • Clinical Science
  • Dietary Intervention
  • Drug Delivery Techniques
  • Genetic Pathways
  • Gut Microbiome
  • Mathematical Modeling
  • Preventative Medicine
  • Public Health
  • Stem Cells
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Editor/Author Biographies

Ashok Kumar Pandurangan is an associate professor in School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Chennai, India. He pursued his PhD in the prestigious University of Madras, Guindy campus, Chennai, India in the area of natural products as a therapeutic agent for colorectal cancer. Later, he was postdoctoral researcher in Center for Cancer research, Children's Hospital Oakland Research Institute, Oakland, California, USA. Further he completed two postdoctoral research programs in Department of Nutrition and Dietetics, Universiti of Putra Malaysia and Department of Pharmacology, University of Malaya, Malaysia. He is currently interested to work in the area of colitis associated cancer (CAC) in murine model. Colitis associated cancer is very common nowadays in developing countries. Ulcerative Colitis (UC) is a type of Inflammatory Bowel Disease (IBD), if untreated can be a risk of developing as colitis associated cancer. Numerous studies are underway to identify drugs that control both inflammation and cell proliferation. So, he is interested in identify some novel drugs from natural source and elucidate the molecular mechanisms involved in the process of curing colitis associated cancer. He published several articles on the effects of natural agents in these areas of interest.

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