A technology miniaturizes complex laboratory processes onto tiny, portable devices, typically the size of a credit card. These chips integrate various functions, including sample preparation, analysis, and detection, making them valuable for fields like diagnostics, genomics, and chemical analysis. LOCs offer rapid results, reduced sample volumes, and cost-effective testing. They find applications in healthcare for point-of-care diagnostics and have potential uses in environmental monitoring and food safety. The technology streamlines laboratory procedures, making it a game-changer in analytical chemistry and biotechnology, offering improved efficiency and convenience.
Published in Chapter:
Emergent Applications of Organ-on-a-Chip (OOAC) Technologies With Artificial Vascular Networks in the 21st Century
Ranjit Barua (Indian Institute of Engineering Science and Technology, Shibpur, India), Nirmalendu Biswas (Jadavpur University, India), and Deepanjan Das (Jadavpur University, India)
Copyright: © 2024
|Pages: 22
DOI: 10.4018/979-8-3693-1214-8.ch010
Abstract
The organ-on-a-chip (OOAC) technology stands at the forefront of emergent technologies, representing a biomimetic configuration of functional organs on a microfluidic chip. This technology synergizes biomedical engineering, cell biology, and biomaterial technology to mimic the microenvironment of specific organs. It effectively replicates the biomechanical and biological soft tissue interfaces, enabling the simulation of organ functionality and responses to various stimuli, including drug reactions and environmental effects. OOAC has vast implications for precision medicine and biological defense strategies. In this chapter, the authors delve into the principles of OOAC, exploring its role in creating physiological models and discussing its advantages, current challenges, and prospects. This examination is significant as it highlights the transformative potential of OOAC technologies in the 21st century and contributes to a deeper understanding of OOAC's applications in advancing medical research.