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What is COVAXIN®

Chapter 18
Handbook of Research on Green Synthesis and Applications of Nanomaterials
COVAXIN ® , India ' s indigenous COVID-19 vaccine by Bharat Biotech is developed in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology (NIV). The indigenous, inactivated vaccine is developed and manufactured in Bharat Biotech's BSL-3 (Bio-Safety Level 3) high containment facility. The vaccine is developed using Whole-Virion Inactivated Vero Cell derived platform technology. Inactivated vaccines do not replicate and are therefore unlikely to revert and cause pathological effects. They contain dead virus, incapable of infecting people but still able to instruct the immune system to mount a defensive reaction against an infection.
Published in Chapter:
Use of Nanoparticles to Combat COVID-19
Ashish Kumar (Lovely Professional University, India) and Abhinay Thakur (Bihar Engineering University, India)
Copyright: © 2022 |Pages: 29
DOI: 10.4018/978-1-7998-8936-6.ch018
Abstract
On January 30, 2020, the World Health Organization declared the unexpected coronavirus pneumonia pandemic a public health crisis of global significance. COVID-19 in its most severe form can cause coagulation issues and acute respiratory distress syndrome. Due to viral modifications and the advent of new viral strains, the efficiency of traditional treatments for viral infections is rapidly fading. To overcome the limitations and to improve anti-viral treatments, integrated scientific research toward nanotechnology treatment investigations are anticipated for probable use in the prevention and/or treatment of viral infections. This chapter focuses on nano-based diagnostics, accompanied by a study of nano-based therapeutics and treatments that have been shown to be effective against viruses that are closely related to SARS-CoV-2. Furthermore, the authors anticipate that nanotechnology-based approaches mentioned throughout this chapter will aid researchers in developing new COVID-19 prevention, diagnosis, and treatment methods.
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