Synergistic, Additive, Antagonistic Effects and the Prooxidant Character of Antioxidants: Interactions in Natural Compounds

Abstract

A detailed discussion of the synergistic, additive, and antagonistic antioxidant interactions is presented as the main subject of the chapter. Relevant and recent data is considered in order to emphasize the importance and actuality of the subject. Also, the prooxidant character of antioxidants is shown as a problem that can be eliminated by utilizing low concentrations of antioxidants and by combining them. The reaction mechanisms involved in the antioxidant interactions produced after a combination of various compounds are stated and exemplified. Thus, the regeneration mechanism, the complexes and adducts formation, and complementary effects are responsible for a specific type of antioxidant interaction. On the basis of the beneficial effects of the combination of natural compounds, the general idea of the advantageous consumption of antioxidants from foods is supported.