Nanomedicine in Human Health Therapeutics and Drug Delivery: Nanobiotechnology and Nanobiomedicine

Nanomedicine in Human Health Therapeutics and Drug Delivery: Nanobiotechnology and Nanobiomedicine

Manzoor A. Mir, Basharat A. Bhat, Bashir A. Sheikh, Gulzar Ahmed Rather, Safiya Mehraj, Wajahat R. Mir
DOI: 10.4018/978-1-7998-5563-7.ch013
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Abstract

The 21st century has seen a massive spring up in the applications of nanobiotechnology. Incorporation of functionalized and modified nanostructures in various biomedical applications has generated significant research interests such as implant and tissue engineering, diagnosis, and therapy, thereby aiding in improvement of human health. The unique properties of nanoparticles including non-toxicity and biocompatibility with a large surface area make it possible to modify their surface with different chemicals including different polymers, antibodies, and drug molecules. Therefore, they are utilized for targeted drug delivery in order to carry drugs and selectively release them in desired tissues which reduces destructive effects on healthy cells. This chapter mainly covers the basic properties of nanoparticles including nanomedicine, their preparation and focuses on their diagnosis, and therapeutic applications in disease including cancer and other challenging ailments.
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Nanobiotechnology

Nanobiotechnology is a multi-vital method that joins nanotechnology and biotechnology to build the properties of restorative operators, e.g., target conveyance of therapeutics by nanoparticles, in a characterized way (Saji et al., 2010). Nanotechnology is one of the recent emerging sciences that employ its applications in different fields ranging from health to the agricultural sciences (Stewart 2016 and Gartland 2018). Nanotechnology is defined by keeping in view the different properties of nanomaterials used in science including physical and chemical properties of nanomaterial and their ability of metabolization(Priyaet al., 2015).

Nanobiotechnology plays an astonishing role in generating many helpful tools to study bio-systems(Qamar et al., 2019). According to the recent research micro-organisms, plant extracts and even fungi generate nanomaterials through various biological pathways(Shafiq et al., 2016; and Verma et al., 2019). These derived nanoparticles are having exceptional properties that are different from the larger molecules of the same element. Because of their greater surface area to volume ratio values nanoparticles differ in properties like electrical, optical, and chemical from those observed in bulk compounds(Roy et al., 2015). By and by, nanomaterials have been broadly investigated for business applications like analytic, treatment and for inquiring about. Another rising field in the present period of cutting-edge nanotechnology and nanorobotics is nanomedicine.

Nanotechnology is a rising field in the advancement of gadgets, materials, or different structures composites having in any event one measurement estimated from 1 to 100 nanometers. In the interim, Biotechnology manages natural subjects that incorporate metabolic and other physiological procedures. A blend of these two advancements, for example, nanobiotechnology assumes a significant job in the assembling and applying numerous valuable devices in the investigation of numerous life forms (Jaison et al., 2018).

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