Computational Framework of Inverted Fuzzy C-Means and Quantum Convolutional Neural Network Towards Accurate Detection of Ovarian Tumors

Computational Framework of Inverted Fuzzy C-Means and Quantum Convolutional Neural Network Towards Accurate Detection of Ovarian Tumors

Ashwini Kodipalli, Steven L. Fernandes, Santosh K. Dasar, Taha Ismail
Copyright: © 2023 |Pages: 16
DOI: 10.4018/IJEHMC.321149
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Abstract

Due to the advancements in the lifestyle, stress builds enormously among individuals. A few recent studies have indicated that stress is a major contributor for infertility and subsequent ovarian cancer among women of reproductive age. In view of this, the present study proposes a two-stage computational methodology to identify and segment the ovarian tumour and classify it as benign or malignant. Using computerized tomography images, the first stage involves image segmentation using inverted fuzzy c-Means clustering, and second stage consists of deep quantum convolutional neural network in order to detect the tumours. The efficacy of the proposed method is demonstrated using in-house clinically collected dataset by comparing the results with the state-of-the-art methods. The experimental results confirm that the proposed approach outperforms the existing fuzzy C means algorithm by achieving the average Jaccard score of (0.65, 0.84, 0.79) (min, max, avg) and Dice score of (0.70, 0.83, 0.77) (min, max, avg), classification result of 78% for benign and 70.03% for malignant tumours. The classification results using the variant of convolutional neural network (CNN) model ResNet16 are compared with the quantum convolutional neural networks (QCNN) and obtained the classification performance of 87.02% for benign and 79.4% for malignant tumours and 84.4% for benign and 77.03% for malignant tumours respectively.
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1. Introduction

In every country of the world, Cancer ranks as one of the leading causes of death. Ovarian cancer is the third most common gynaecological cancer in Indian women. From age 35, the risk of Ovarian cancer increases and reaches a peak between 55-64 (Labidi-Galy et al., 2012). Ovarian cancer has the worst prognosis as it is diagnosed in advanced stages such as stage III or IV. Since the cause of ovarian cancer is unknown, effective screening strategies for it are not found. The process of ovarian cancer segmentation using MRI and CT images has received considerable amount of attention in biomedical image segmentation and classification. As per the National Cancer Institute statistics, around 19,880 people were diagnosed with ovarian cancer and approximately 12,810 deaths were due to ovarian cancer by 2022 (National Cancer Institute, 2023). Greater efforts have been made for the early detection of ovarian cancer. Computer-aided diagnosis system is less time consuming and also gives more accurate and reliable results. With the advancement in the Image Processing techniques, Machine Learning algorithms, Deep Learning models and more importantly the computational devices, it is more evident to there is tremendous developments in the CAD systems. In the literature there are many works which has focused on the development of CADs using various medical images (Alharbi & Tchier, 2017; Bron et al., 2017; Chang et al., 2017; Chen et al., 2014; de Carvalho Filho et al., 2017; Nishio & Nagashima, 2017; Wang et al., 2016; Yilmaz et al., 2017). There are CADs which are developed for diagnosing the various cancer such as liver, brain, breast etc using CT and other modalities using Image Processing techniques (Chang et al., 2017), automatic image analysis for detection of various cancers and classifying as benign and malignant using classical machine learning algorithms (Nishio & Nagashima, 2017), there are many works which are carried out for the detection of ovarian cancer with the help of Deep Convolutional Neural Networks (Alharbi & Tchier, 2017; Bron et al., 2017; Chen et al., 2014; de Carvalho Filho et al., 2017; Suzuki, 2017; Wang et al., 2016; Yilmaz et al., 2017).

The rest of the paper is organized as follows. Section 2 presents the literature survey, with the detailed methodology and the description of algorithms is presented in Section 3, with the experimental results reported in Section 3, Section 4 provides conclusion.

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